R&D

R&D

Research and development is a serious investment in time and money โ€“ on average, large multinational drug companies spend 17%of their revenues of R&D, while it takes ten years on average to bring a new drug to market. The latest release of DrugBank contains over 13,000 approved drug entries that are available in the global market. According to a report from the World Health Organization there are more than 10,000 types and 1.5 million pieces of medical devices or equipment available today.

Myles Whiting, design team leader at medical device company Owen Mumford, echoes the importance of this collaborative effort in research and development, โ€œProduct designers must work with marketing teams to establish unmet market and customer needs, then marketing teams interpret and deliver market context and customer needs to the engineers, who then have the ability to process this into measurable design input. The research and information is gathered, this is then accumulated into a brief which the designer uses to address the market or customer need.โ€

The Federal Institute for Drugs and Medical Devices (Bundesinstitut fรผr Arzneimittel und Medizinprodukte) (BfArM) is the body that regulates drugs and medical devices in Germany. Technological advancements are proving key in their advancement into the research of medical devices. The emergence of โ€˜big dataโ€™ has โ€œincreased quantities of data on offer to the BfArM, giving them the opportunity to quickly gain more insights on medical device risks in the future.โ€ The number of medical device incident reports received by the BfArMper year has approximately tripled in the past ten years. In 2017, almost 14,000 reports were received, and this number continues to grow thanks to the amount of the amount of โ€˜big dataโ€™ information gathered.

Technological advancements have reduced the cost of research and development โ€“ helping to accelerate investment in life sciences โ€“ while also creating new opportunities for product innovations as the Fourth Industrial revolution blurs the boundaries between the biological, physical and digital worlds. According to a report by KPMG, the cost of drug R&D will drop by 2030, leading to numerous benefits for both the industry and consumer in terms of cost savings.

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Benefits of working with us

Experience

We have over a decadeโ€™s worth of experience as a leading talent partner in Life Sciences & Pharma.

Network

A vast, global network of the best, in-demand professionals, working with the worldโ€™s largest Life Sciences institutions, to take drugs, devices and therapeutic applications through from conception to completion.

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Our award-winning talent specialists offer bespoke, tailored guidance on the latest hiring trends and industry news to help you achieve your goals.

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R&D Jobs

Sr. RA/Associate Scientist Downstream Process Development

Client: Our client is an emerging gene editing company targeting RNA. Job Summary: We are looking for an experienced AAV Production Senior Research Associate/Associate Scientist to join our team. This role focuses on leading AAV production, optimizing downstream processes to improve yield, quality, and consistency. The ideal candidate will have extensive experience in AAV production using both adherent and suspension cell platforms and a proven ability to optimize protocols for scale-up and purification. Collaboration and teamwork are essential for this role. Key Responsibilities: AAV Production and Process Development: Develop and scale AAV production processes, including gradient and affinity column purification. Perform cell culture for AAV production (adherent and suspension). Operate bioreactors, AKTA systems, and automated buffer exchange systems. Improve purification methods to streamline workflows. AAV Characterization and Assay Development: Conduct assays to evaluate AAV performance in mammalian cell lines. Perform ddPCR, sequencing, and ELISA-based assays for AAV characterization. Analyze AAV stability, aggregation, and particle-to-infectivity ratios. Optimize purification and buffer exchange protocols. Inventory, Documentation, and Workflow Management: Manage lab inventory and ensure efficient use of resources. Maintain accurate records and author SOPs and production batch records. Produce AAV lots for research and preclinical studies. Collaboration and Training: Train and guide team members in AAV production techniques. Support viral transduction for in vitro and in vivo applications. Collaborate with cross-functional teams to meet project goals. Lead troubleshooting efforts and ensure protocol compliance. Qualifications: Education: Bachelor's or Master's in Molecular Biology, Biochemistry, Virology, or a related field, or equivalent experience. Experience: 4+ years of hands-on industry experience in AAV production, with expertise in both adherent and suspension HEK293 cells. Proven track record in scale-up production and purification processes. Technical Skills: Proficiency with AKTA, bioreactors, and molecular biology techniques (e.g., DNA/RNA/protein isolation, cDNA synthesis, RT-PCR, qPCR, digital PCR, western blot, immunofluorescence). Leadership: Ability to manage and mentor team members in a production environment. Analytical Skills: Strong troubleshooting and optimization skills for viral vector production. Compensation: $115,000-$130,000 base salary, depending on years of experience.

US$115000 - US$130000 per year
San Francisco
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Director, In Vivo Biology

Title: Director, In Vivo Biology EPM is partnered with true light in the genetic medicine biotech space that is looking for a Director of In Vivo Biology to lead and design all in vivo studies. This pivotal role will drive advance the proprietary receptor-targeted genetic medicine platform and preclinical pipeline programs. This individual will manage the In Vivo Biology team, including scientists and research associates, and collaborate with leaders across various departments. Additionally, this individual will create innovative disease models to support Proof-of-Concept and IND-enabling studies, utilizing a strong background in genetic diseases across multiple therapeutic areas. Role Overview: - Spearhead innovative in vivo biology studies. - Craft strategic direction within pharmacology and drug development teams. - Lead by example fostering intellectual growth among your team members. Qualifications & Experience Required: - PhD required (Pharmacology, Biology or related field) focusing on in vivo biology; advanced degree preferred Experience: - Minimum eight years' industry experience specializing in either: Pharmacogenetics Drug Metabolism and Pharmacokinetics (DMPK) - At least three years commanding leadership roles Key Skills Insight: 1. Bring deep understanding of genetic variation's impact on drug response - vital for personalized medicine advancements. 2. Leverage extensive knowledge across biotechnological applications ensuring cutting-edge project execution. 3. Show adeptness at employing experimental planning methodologies enhancing research efficiency and outcomes accuracy. 4. Strong expertise in in vivo models, PK/PD assessment, and genetic medicine delivery technologies (e.g., CRISPR, ASOs, siRNAs, or biologics). 5. Theoretical grounding coupled practical know-how will empower robust design interpretation trials aimed toward transformative gene therapies tailored real-world application potentialities If interested, please apply in now!

US$200000 - US$225000 per year
San Francisco
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Senior Quality Engineer

Overview: EPM is hiring on behalf of a leading medical device manufacturer recognized for its innovation and excellence in producing active medical devices and software solutions. This hybrid position offers a unique opportunity to play a pivotal role in ensuring the quality and compliance of cutting-edge products that advance healthcare worldwide. Key Responsibilities: Oversee and enhance quality assurance processes for active medical devices and associated software, ensuring compliance with FDA, ISO 13485, IEC 62304, and other applicable global standards. Participate in product lifecycle activities, including design verification, validation, and risk management, to ensure quality integration from concept to post-market. Lead root cause analysis, non-conformance investigations, and corrective and preventive action (CAPA) activities. Collaborate cross-functionally with R&D, manufacturing, and regulatory teams to ensure adherence to quality standards throughout development and production. Conduct and support internal and external audits, including supplier audits, ensuring robust documentation and adherence to applicable regulations. Provide quality input for software lifecycle management, including configuration control, validation, and cybersecurity compliance. Stay updated on industry trends, emerging regulations, and best practices to guide continuous improvement initiatives. Mentor and train junior QA staff on best practices, standards, and regulatory requirements. Qualifications: Bachelor's degree in Engineering, Life Sciences, or a related field (Advanced degree preferred). Minimum of 5 years of experience in quality assurance for active medical devices and software. Strong knowledge of FDA regulations (21 CFR Part 820), ISO 13485, IEC 62304 (software lifecycle), and risk management standards such as ISO 14971. Experience with software quality assurance, validation, and cybersecurity considerations for medical devices. Proven track record of working in hybrid or cross-functional environments with a focus on quality and compliance. Excellent problem-solving, analytical, and communication skills. Certifications in quality management or auditing (e.g., ASQ Certified Quality Engineer, Certified Quality Auditor) are a plus.

Negotiable
United States of America
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Senior Engineer

Your Tasks Are you ready to leverage your electronic engineering expertise in a whole new way? Working within a team of global experts, put your electronics expertise to work to help companies all over the world maintain compliant products and development systems. Explore new possibilities and apply today! As a technical assessor, you'll perform desk-top evaluations, ensuring that the foundations of the product and configuration management fundamentals have been achieved or are being maintained. On-site, you'll become a technical auditor, using your analytical skills to uncover hidden issues, diving deep into configuration management systems to ensure they're robust, effective, and suitable to maintain product compliance. Become a sought-after expert, helping organizations achieve excellence, drive continuous improvement, and make a tangible impact on product quality on a global scale. Does this sound like the perfect opportunity to take your career to the next level? See if you have what it takes below. Main Duties & Responsibilities: Performing remote and onsite assessments of client's management systems. Performing remote and onsite assessments of client's design and manufacturing controls and processes. Supporting customers to ensure their products are compliant with certification requirements. Presenting findings to clients and senior management, clearly explaining the requirements and timescales. Tracking and closing findings with clients and senior management, where appropriate. Documenting audit results and observations, and updating supporting documentation. Working closely with the certification operational team to ensure customers' compliance with certification requirements. Attending technical committee meetings, client meetings, and industry committees. Delivering training to clients.

Negotiable
Fareham
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Associate Director/Director Analytical Sciences & Technology

Our client is a research organisation that develops vaccines and biologics. They are currently looking for a leader for their Analytical Sciences & Technology team to drive the development and implementation of analytical controls activities. Responsibilities: Develop and manage strategies for the entire lifecycle of analytical methods, ensuring compliance with regulatory standards. Provide strategic leadership for AS&T and QC systems, overseeing processes, programs, and procedures. Collaborate with various departments to support scientific analysis and manage external laboratory activities. Ensure QC laboratory operations comply with GMP standards, and review and approve all analytical documents. Monitor AS&T and QC program performance, address laboratory issues, and drive continuous improvement. Lead and mentor the AS&T team, contributing to strategic planning and quality standards as part of the Quality Leadership Team (QLT). Requirements: Bachelors in Science, Engineering or related technical field. Masters or PhD preferred. At least 10 years of experience in CMC, Analytical Sciences, Quality Control or related Familiar with regulatory requirements Strong GMP knowledge and experience Strong leadership experience Strong and effective communication skills If you are interested, please apply with your CV attached.

Negotiable
Singapore
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Formulation Sciences Associate Director/Director

Our client is a research organisation that develops vaccines and biologics. They are currently looking for a leader for their Formulation Sciences team to drive the product development strategies of their pipeline products. Responsibilities: Spearhead the development of pipeline products, including vaccines, monoclonal antibodies, and recombinant proteins. Manage the DP manufacturing team and ensure production equipment and processes are qualified. Oversee the introduction of new pipeline candidates into manufacturing, including production changeovers and equipment commissioning. Lead GMP-driven projects, address CAPA, investigate deviations, and enhance manufacturing technologies. Ensure the team adapts to evolving business needs and maintain high team engagement and performance. Work with various departments, implement innovative solutions, and drive continuous improvement in drug product development. Requirements: Bachelors in Chemistry, Biology, Pharmacy, Engineering or related Pharmaceutical Sciences. Masters or PhD preferred. At least 10 years of industry experience with 5 years of leadership experience Experienced in CMC biopharmaceutical development Knowledge in Good Manufacturing Practices (cGMP); Great communication skills If you are interested, please apply with your CV attached.

Negotiable
Singapore
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Associate Scientist I/II Analytical Development

Summary: Join this innovative team and fast growing Biotech dedicated to advancing pharmaceutical research and development. Seeking a motivated and skilled Associate Scientist with experience developing analytical methods for small molecule drug products to contribute to 2025 milestones. Key Responsibilities: Conduct laboratory activities with minimal supervision, including analyzing raw materials, in-process materials, and finished pharmaceutical products for quality, safety, purity, strength, and identity. Independently set up and operate lab equipment, prepare reagents, solvents, and solutions for analytical and formulation activities. Maintain accurate records in lab notebooks and process analytical data using lab equipment such as HPLC/UPLC. Support the manufacture of small molecule drug products and prepare samples for blend uniformity. Perform equipment qualification and calibrations as directed. Execute approved method transfer protocols. Assist in training other scientists and perform additional tasks as assigned. Participate in project activities, support project timelines, and contribute to team objectives. Establish and maintain effective relationships with team members. Conduct lab work in accordance with SOPs & STPs, following corporate safety rules and procedures. Comply with all corporate guidelines and policies. Qualifications: Bachelors in Chemistry, Pharmacy, or related fields with at least 3 years of experience in Pharmaceutical R&D, or M.S. with 1-2 years of experience in the Pharmaceutical industry. Proven ability and/or experience with compendial test methods or pharmaceutical manufacturing equipment. Understanding of pharmaceutical equipment and computerized systems for operation and troubleshooting. Specific experience with analytical and/or process equipment used in laboratories such as HPLC, IR/FTIR, UV-Vis AA, powder blender, etc. Experience with Empower software Knowledge and understanding of FDA cGMP requirements as they apply to the pharmaceutical industry. Effective English written and oral communication skills, with the ability to write short technical documents such as memos, laboratory investigations, protocols, and reports.

US$60000 - US$85000 per year
Florida
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Lead Scientist, Cell Line Development

Job Description Position Summary This full-time, on-site role in Minneapolis, MN, is for a Lead Scientist specializing in Cell Line Development. Key duties include overseeing cell line development and optimization, designing and conducting experiments, analyzing data, and collaborating with cross-functional teams to propel innovation and product development in biotechnology. Responsibilities: Lead the establishment and management of our cell line development division, creating workflows for stable cell line generation. Develop and optimize mammalian cell lines (e.g., CHO, HEK293) for clients. Keep abreast of industry trends by evaluating and integrating cutting-edge technologies. Write technical reports, SOPs, and regulatory documents. Represent the company at external events and cultivate strategic partnerships. Qualifications: PhD (preferred) or MS in Molecular Biology, Cell Biology, Biotechnology, or a related field. Extensive experience in cell line development with a proven track record of success. Expertise in transfection techniques, clone screening, and high-productivity cell line optimization. Knowledge of cGMP, 21 CFR Part 820, and ISO quality standards. Entrepreneurial mindset with strong leadership and strategic planning abilities. Excellent communication skills for interacting with stakeholders at all levels.

Negotiable
Minneapolis
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Director, Microbiology

Summary: This pioneering biotech company specializing in innovative therapies for infectious pulmonary diseases is seeking a highly skilled and experienced Director of Microbiology who is passionate about improving the quality of life for patients through cutting-edge research and development. Key Responsibilities: Design, oversee, and publish outsourced or collaborative studies for drug programs Monitor and ensure data quality control, and manage data dissemination through a database Clearly and effectively communicate study results and their impact at both internal and external meetings Engage in scientific writing for reporting, data management, and adherence to standard operating procedures Experience with Good Clinical Practice (GCP) and clinical trials is required. Ensure compliance with current Good Manufacturing Practices (cGMP) and Health, Safety, and Environmental policies. Oversee the execution of microbiology data collection through clinical trials. Plan, execute, and summarize microbiology studies on new drug substances, focusing on clinical and pre-clinical models. Collaborate with contract labs to perform advisory functions related to microbial and antibiotic materials. Responsible for authoring/reviewing the microbiology sections of IND & NDA's Lead investigations into Out-of-Specification (OOS) and Out-of-Expectation (OOE) results, manage change controls, deviations, and Corrective and Preventative Actions (CAPA), and support laboratory inspections and audits. Qualifications: Ph.D. or Master's degree in Microbiology, Biology, or a related field. Minimum of 8-10 years of experience in microbiology within the biotech or pharmaceutical industry. Proven leadership and team management skills. Extensive knowledge of cGMP, regulatory requirements, and quality control processes. Strong problem-solving abilities and technical expertise. Excellent communication and interpersonal skills. Previous exposure to FDA pulmonary or anti-infective programs is a major plus. Pharmacokinetics experience is also a plus.

US$185000 - US$250000 per year
Westlake Village
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Principal Scientist Analytical

Position Summary: A cutting-edge Biotech is looking to expand their Analytical team by bringing on a Principal Scientist. Key Responsibilities: Lead and oversee analytical development projects for biologics and CGT, from early to late-stage development. Design and implement robust analytical strategies to support product development and regulatory submissions. Develop and validate analytical methods for the characterization and quality control of biologics and CGT products. Collaborate with cross-functional teams, including R&D, manufacturing, and regulatory affairs, to ensure seamless project progression. Mentor and manage a team of scientists, fostering a collaborative and innovative work environment. Stay current with industry trends and advancements in analytical technologies and methodologies. Prepare and review technical reports, regulatory documents, and scientific publications. Qualifications: Ph.D. in Biochemistry, Molecular Biology, Analytical Chemistry, or a related field. Minimum of 4 years of industry experience in analytical development for biologics and CGT. Proven experience in early and late-stage development projects. Strong leadership and internal management skills, with a track record of mentoring and developing scientific talent. Expertise in analytical techniques such as HPLC, mass spectrometry, ELISA, and cell-based assays. Excellent problem-solving skills and the ability to work effectively in a fast-paced, dynamic environment. Strong communication and interpersonal skills, with the ability to collaborate effectively with cross-functional teams.

US$150000 - US$170000 per year
Los Angeles
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Scientist II Analytical Development

SUMMARY This leading global pharmaceutical company is looking for a strong Analytical Scientist to join their R&D team in support of one of the fastest growing portfolios of pharmaceutical drug products across a wide range of therapeutic areas. The ideal candidate will have a Ph.D. with at least 2-3 years of hands-on experience with solid orals/semi-solids for small molecules OR Masters +8-10 years. RESPONSIBILITIES Lead analytical development activities while providing supervision, training, & leadership to the jr. chemists. Identifies analytical test method goals to support the different product development stages and develops accurate and robust analytical test methods Performs complex analytical testing with accuracy and efficiency Provides a high level of experimental design and data interpretation Participate in cross functional meetings and provide input on strategy implementation for various projects where needed. Author & review relevant technical documents/SOP's & FDA submissions QUALIFICATIONS Ph.D. in Pharmaceutical Sciences (Or equivalent/relevant degree) with 2-3 years of small molecule analytical development experience in the pharma industry OR M.S. +8-10 years. Expertise in key analytical techniques such as HPLC, LC-MS, dissolution studies, XRPD, DSC, IR, etc. Strong communication skills (written & verbal) Experience with additional dosage forms (nasal, topical, injectable, liquid solutions, etc.) is a major plus!-Solid Orals are a MUST.

US$90000 - US$130000 per year
California
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Director, Antibody Discovery (In Vitro)

Overview: As the Director of Antibody Discovery - In Vitro, you will be an excellent addition to our fast-paced and exciting team of committed scientists. Utilize your depth and breadth of knowledge in antibody discovery, optimization, and program progression through discovery towards IND. With your experience and expertise, you will lead biologics programs from early discovery through candidate selection to IND, and activity that incorporates in vitro based discovery platforms such as yeast and phage display. Leadership: Utilize your deep knowledge of antibody discovery and optimization using in vitro methods such as yeast, phage, or mammalian display. (Yeast Display expertise strongly preffered) Guide the mining and triaging of antibody repertoires to advance therapeutic candidates. Provide strategic insights on candidate profiles, optimization approaches, and progression from lead to candidate. Incorporate NGS and Sanger sequencing for repertoire and clonal analysis. Drive efficient workflow progression and foster innovation within the team. Engage with external networks to evaluate new opportunities and partnerships. Program Leadership: Lead programs from discovery to IND, integrating early research and candidate selection. Possess detailed knowledge of the biologics process from discovery to pre-IND. Act as an ambassador for the biologics department, providing scientific input to project teams. Collaborate with internal and external groups to ensure efficient and transparent progression of molecules. People Leadership: Oversee the performance and results of a significant research function with managerial responsibilities. Adopt an enterprise mindset to inform resourcing and prioritization across the portfolio. Lead a team of skilled scientists, fostering their development and inspiring a team-centric mindset. Ensure effective resourcing and lead in-lab discovery and optimization campaigns, including affinity maturation and developability. Minimum Requirements/Qualifications: PhD with 10+ years of experience, MS with 16+ years, or BS with 18+ years. 9 years of industry experience and 9 years of managerial experience with a deep expertise in in Vitro Antibody Discovery (Yeast Display experience highly desirable) Expertise in a scientific area and up-to-date knowledge of scientific advancements. Ability to manage workload independently and drive research strategy.

Negotiable
Boston
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