Overview:
As the Director of Antibody Discovery - In Vitro, you will be an excellent addition to our fast-paced and exciting team of committed scientists. Utilize your depth and breadth of knowledge in antibody discovery, optimization, and program progression through discovery towards IND. With your experience and expertise, you will lead biologics programs from early discovery through candidate selection to IND, and activity that incorporates in vitro based discovery platforms such as yeast and phage display.
Leadership:
- Utilize your deep knowledge of antibody discovery and optimization using in vitro methods such as yeast, phage, or mammalian display. (Yeast Display expertise strongly preferred)
- Guide the mining and triaging of antibody repertoires to advance therapeutic candidates.
- Provide strategic insights on candidate profiles, optimization approaches, and progression from lead to candidate.
- Incorporate NGS and Sanger sequencing for repertoire and clonal analysis.
- Drive efficient workflow progression and foster innovation within the team.
- Engage with external networks to evaluate new opportunities and partnerships.
Program Leadership:
- Lead programs from discovery to IND, integrating early research and candidate selection.
- Possess detailed knowledge of the biologics process from discovery to pre-IND.
- Act as an ambassador for the biologics department, providing scientific input to project teams.
- Collaborate with internal and external groups to ensure efficient and transparent progression of molecules.
People Leadership:
- Oversee the performance and results of a significant research function with managerial responsibilities.
- Adopt an enterprise mindset to inform resourcing and prioritization across the portfolio.
- Lead a team of skilled scientists, fostering their development and inspiring a team-centric mindset.
- Ensure effective resourcing and lead in-lab discovery and optimization campaigns, including affinity maturation and developability.
Minimum Requirements/Qualifications:
- PhD with 10+ years of experience, MS with 16+ years, or BS with 18+ years.
- 9 years of industry experience and 9 years of managerial experience with a deep expertise in in Vitro Antibody Discovery (Yeast Display experience highly desirable)
- Expertise in a scientific area and up-to-date knowledge of scientific advancements.
- Ability to manage workload independently and drive research strategy.
